Artificial osseous defects were created on mandibles of dry skulls. All subjects provided subjective assessments on factors, such as tongue coating, halitosis, salivation, and their abilities to perceive taste and smell. 2019 Journal Citation Reports (Clarivate Analytics): 1/91 (Dentistry, Oral Surgery & Medicine) Online ISSN:1600-0757. Actions. The aim of this short-term study was to compare the effect of delmopinol HCl 0.2% and chlorhexidine digluconate 0.2% rinses on the development of dental plaque, the healing of experimental gingivitis, and the salivary microbiology. No significant difference was found between the two sprays. The Journal Impact measures the average number of citations received in a particular year (2019) by papers published in the journal during the two preceding years (2017-2018). The study indicates that subcutaneous injections of rhIL-11 were able to slow the progression of attachment and radiographic alveolar bone loss in a ligature-induced beagle dog model. The results demonstrated that a mouthrinse containing CK-0569A prevented the colonization of motile + curved rods and spirochetes in developing plaque. Although patients with dressing frequently experienced eating difficulty, most stated a psychological feeling of protection and well-being with its use. They received a thorough dental prophylaxis prior to the test period. ISSN: 0022-3492. The Journal of Periodontology publishes articles relevant to the science and practice of periodontics and related areas. Pain assessment was made according to a structured, categorized scale (0 = no pain; 1 = mild pain; 2 = moderate pain; and 3 = severe pain). Almost all subjects showed relatively high proportions of Prevotella intermedia, Campylobacter rectus, motile organisms, and spirochetes. All 3 treatment groups lost significantly less attachment and retained significantly more bone than did the placebo group. Sinus burs and condensers of increasing width are used in conjunction with pliable atraumatic bone grafting mixture and hydraulic pressure from a surgical handpiece. © John Wiley & Sons A/S. Rompen EH, Goffinet GH, Nusgens B (1999;70:1144-1152), The Basal phosphorylation sites of endothelial nitric oxide synthase at serine (Ser)1177, Ser116, and threonine (Thr)495 in rat molar epithelial rests of Malassez, Re: Rationale for use of antibiotics in periodontics. Although carefully collected, accuracy cannot be guaranteed. I. Other titles: JIAP Start year: 1999 Frequency: Quarterly Country: England Language: English Topics: Periodontal Diseases Periodontics Publisher: London : FDI World Dental Press Ltd, 1999-Publication type: Periodicals. Plasma Levels of Tumour Necrosis Factor-α in Patients With Chronic Periodontitis and Type 2 Diabetes. Data were compared by factorial analysis of variance and a post-hoc Tukey honestly significant difference (HSD) test. Highly effective antimicrobials should also prevent recolonization of periodontopathogens. Furthermore, rinsing twice daily with 0.1% solution CK-0569A significantly reduced the amount of dental plaque formed and retarded the development of gingivitis. The protective role of this cytokine against different diseases has been demonstrated in several studies. Previous studies have demonstrated the potential beneficial effects of post-surgical rinsing with 0.2% chlorhexidine. Pocketing was also significantly less after chlorhexidine, although in clinical terms the difference was small. There was an increase in amount of perceived postoperative pain and gingival swelling with the use of the chlorhexidine rinse, but no difference in the number of pain pills taken during this study. Linear measurements for all defects revealed no statistical differences between bone sounding, radiography, and CBCT. J Periodontol. The aim of this study was to evaluate the levels of cystatin C, interleukin-1beta (IL-1beta), and tumor necrosis factor-alpha (TNF-alpha) in the total saliva and gingival crevicular fluid (GCF) of periodontally healthy children (PHC) and children with gingivitis (CG) who were between 11 and 16 years old. Delmopinol has been shown to possess plaque inhibitory activity in several previous studies. (ABSTRACT TRUNCATED AT 250 WORDS). Journal Impact. CBCT scanning, periapical radiography (PA), and direct measurements using a periodontal probe were compared to an electronic caliper that was used as a standard reference. The purpose of this study was to describe the microflora and clinical parameters of young adults with minor to moderate periodontitis during treatment for a period of 1 year. GCF was sampled 0, 2, 4, 6, 8, and 12 hours post-rinsing. At baseline all subjects received a clinical examination consisting of an intraoral soft tissue, plaque (Turesky modification of Quigley-Hein plaque index), and gingival index (modified gingival index) evaluations, and received a thorough oral prophylaxis. 2015;42(Suppl 16):S59–S70. Gingival concentrations of both cytokines were significantly lower in gingiva adjacent to a > or = 6 mm pocket. Therefore, the aim of this study was to compare CBCT measurements of periodontal defects to traditional methods. 9. Previous studies have indicated that spray delivery of chlorhexidine is both effective and acceptable. The effects of topical ketorolac tromethamine mouthrinse (0.1%) on gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) concentrations were investigated in a 6-week, randomized, double-blind, placebo-controlled, parallel group, single center study of 42 patients with moderately advanced chronic adult periodontitis. The purpose of this investigation was to determine if recombinant human interleukin-11 (rhIL-11), known to downregulate several inflammatory modulators, has the ability in subcutaneous administration to reduce the rate and/or extent of periodontal attachment loss and radiographic bone loss in a ligature-induced periodontal disease beagle dog model. Experimental rats were sacrificed at preselected time intervals and autoradiographic procedures were performed subsequent to conventional histologic studies. Impact Factor. A statistically significant decrease in the probing depth occurred as a result of ultrasonic scaling; however, no significant changes in the PI or GI occurred. PREVIOUS STUDIES have shown that 125I absorptiometry gives an accurate and sensitive measure of alveolar bone mass. Treatment of the purified sample with pronase E reduced remarkably either the hemagglutinating activity or the precipitation reaction with proline-rich glycoprotein in human parotid saliva, suggesting that the active site may be present on the peptide moieties. 2007. On the basis of the clinical distribution of lesions, the histopathology, and direct and indirect immunofluorescent tests, the lesions were definitively diagnosed as cicatricial pemphigoid. Tools. Nine patients who required two periodontal surgeries in two posterior areas were selected. Attachment levels and bone height were also measured. H-Index, Successful case management coupled with a high degree of patient acceptance prompted the authors to continue to perform full dentition periodontal surgery with the aid of conscious sedation plus local anesthesia. Published by John Wiley … The -1082*A allele was significantly more common in children with gingivitis; 49% versus 37% in controls (P = 0.01). The results showed little change of the CFUs by either single application of SnF2 or saline. Bonito AJ, Lux L, Lohr KN (2005;76:1227-1236), Insulin I 125 Distribution Within Oral Tissues*, Relationship Between Alveolar Bone Measured by 125 I Absorptiometry With Analysis of Standardized Radiographs: 2. IL-11, IL-6, and RANTES concentrations were significantly correlated with sulcular depth. 2018 Jul ; 89 (7) :737-742. A method is described for registering minute changes in bone mass in restricted parts of the jaw. Gingival concentrations of IL-11 and IL-17 are different in diseased gingiva adjacent to 3, 4 to 5, and > or = 6 mm pockets, suggesting that their concentrations change as a consequence of the progression of gingivitis to periodontitis and that both cytokines could have a significant role in this progression. ISSN: 0022-1554. Delmopinol, a 3-alkyl substituted N-hydroethyl morpholine, has shown potential as a mouthrinse for the management of dental plaque and treatment of gingivitis. Within the limitations of this 3-day "de novo" plaque formation study, the two sprays were not as effective as the mouthwash in plaque inhibition. II. Plaque index, gingival index, and crevicular fluid flow measurements were obtained at baseline, and at 1 and 2 weeks after surgery. Ninety volunteers were enrolled into a single-blind, randomized, three-group parallel study. The control insert without any antibacterial agent was applied in a selected pocket in a different quadrant for each patient. Overall, all three modalities are useful for identifying interproximal periodontal defects. Some major contraindications for the immediate implant are acute periodontitis and active infection. Peri‐implant diseases, including peri‐implant mucositis and peri‐implantitis, were first defined and described at the First European Workshop on Periodontology in Ittingen in 1993. Journal Impact Prediction System provides an open, transparent, and straightforward platform to help academic researchers Predict future Metric and performance through the wisdom of crowds. A 0.2% chlorhexidine mouthwash (10 ml for 1 minute twice daily) was prescribed postoperatively for all patients. Clinical findings were improved at both PT-01 and control sites, but the improvements were much more significant at PT-01 sites, in particular BOP and PD, than at control sites. The basal production of NO by eNOS in the ERM is modulated by phosphorylation of eNOS at Ser1177 and Ser116 residues, while the basal activity of the eNOS is not influenced by phosphorylation of eNOS at Thr495 residue. Risk indicators for attachment loss. Bacterial samples were obtained after 7 and 14 days of trial. Treatment administration and clinical and radiographic evaluations were performed in a masked fashion. © John Wiley & Sons A/S. Mean PD reduction from baseline to 3 months was 2.13 +/- 0.35 mm and 2.53 +/- 0.52 in groups 1 and 2, respectively. Abbreviation: J Clin Periodontol. Data provided are for informational purposes only. The binding of the radioactive MGP to bacterial cells was specifically inhibited by galactose, lactose and N-acetyllactosamine. These findings strongly suggested that a lectin-like substance may be present on the bacterial cell surface. Clinical parameters were recorded at baseline and 1, 2, and 3 months; they included modified gingival index, modified sulcus bleeding index, probing depth (PD), and clinical attachment level (CAL). In no instance was a major complication noted. After sampling, biochemical analyses were performed using latex particle-enhanced turbidimetric immunoassay for cystatin C and enzyme-linked immunosorbent assay for IL-1beta and TNF-alpha. Interleukin (IL)-10 is an anti-inflammatory cytokine. Successful antimicrobial treatment following periodontal surgery depends upon the elimination and suppression of wound associated microorganisms. Magiscan*, Misch KA, Yi ES, Sarment DP. Both chlorhexidine regimens significantly (P less than or equal to 0.008) increased the % of Gram-positive facultative cocci compared to water irrigation at 3 months. The scope of Journal of Periodontology covers Stress leads to activation of the hypothalamic-pituitary-adrenal axis, resulting in increased cortisol release. Research Hotspot and Yet there is little research to establish periodontal bone measurement using CBCT as a valid method. J Clin Periodontol 2005; 32: 412-416. doi: 10.1111/j.1600051X.2005.00689.x. Evidence on the clinical performance of recently introduced dental implants in titanium-zirconium alloy is sparse. J Periodontol 1996;67:1103-13. Few black pigmented Bacteroides or Actinobacillus actinomycetemcomitans were found prior to surgery or any time postoperatively. After the baseline visit all patients received a supra- and subgingival oral prophylaxis. Clinical examination of plaque and gingivitis was repeated 4, 7 and 14 days after the start of the no-toothbrushing periods. Chlorhexidine rinse also significantly (P less than or equal to 0.008) reduced log10 CFU of black-pigmented Bacteroides at 6 months. Quantitatively, the distribution of bacteria, after 2 and 6 weeks of mouthrinse use, was consistent with a young, less mature plaque. Gingival fibroblasts were stimulated with 10(-7) or 10(-9) M hydrocortisone for 24 hours; untreated cells served as controls. The mean concentration of 0.5% AZM in gingival crevicular fluid was estimated by reverse phase high performance liquid chromatography. The maxillary premolar area showed the highest survival rate (96.2%). Forty subjects rinsed with either 15 ml of CHX rinse or control (sterile water) for 30 seconds, expectorated and immediately rinsed again for 30 seconds. Journal of Periodontology Impact Factor IF 2020|2019|2018 - … Citing Literature . Patients were classified in two groups. The chlorhexidine rinse significantly reduced the amount of plaque at both 1 and 2 weeks, and gingival inflammation remained similar to base line measurements at 2 weeks. Two nondiabetic control animals were also injected with the tracer. 2018;89(Suppl 1):S9-S16. The isoelectric point of the purified sample was 8.5 to 9.0. After 3 days, the CHX mouthwash group had a mean Q&H PI of 1.17 compared to 1.41 for the 0.2% CHX spray and 1.49 for the 0.12% CHX spray. A 2-factor repeated measure ANOVA was performed on each parameter after the Baseline 2 evaluation. which is located in the United States. Edited By: Jørgen Slots. Gingival index (GI), plaque index (PI), and probing depths (PD) were recorded and an ultrasonic scaling was performed (Baseline 1). To the best of our knowledge, this study represents the first evaluation of cystatin C in the gingival disease mechanism in children. Abbreviation: J Indian Soc Periodontol. Because blood and debris arising from S&RP could inactivate CHX and decrease its antimicrobial effect, patients were evaluated throughout their appointment. EKE, Wenche S. Borgnakke, Jasim M. Albandar, Measurement and Distribution of Periodontal Diseases, Burt and Eklund's Dentistry, Dental Practice, and the Community, 10.1016/B978-0-323-55484-8.00015-0, (171-188), (2021). Fisher's exact test and chi square test demonstrated that in the screening group, duration of immunosuppressive treatment and oral hygiene scores were associated both with the prevalence and the high GO scores (P (1) (DIT) <0.0001; P (2) (DIT)=0.0023; P (1) (hyg)=0.0084; P (2) (hyg)=0.0068). The presence of subjective and objective side effects of the groups was compared via use of chi2 and Fisher exact tests. The gingival health of each animal was measured by recording the presence or absence of gingival inflammation, plaque, and bleeding upon probing. At each site the 125I absorptiometry measurements were made at the same location by fixing the photon source to a prefabricated precision-made occlusal splint. Journal of Periodontology is a peer-reviewed scientific journal. Utilizing mean GCF PGE2 concentrations at days 0 and 14 as covariates, no significant differences were observed in adjusted mean PGE2 levels at days 28 and 42 between the study groups (ANCOVA, P > 0.05). Citescore, To date, 10,000 cases have been completed in this manner. Plaque samples were analyzed from 105 patients at baseline, 93 patients at 3 months and 88 patients at 6 months. It is available in different delivery devices. Alterations in the expression of MMP-1, -2, -3, -7, -11 and TIMP-1 and -2 were evaluated using real-time polymerase chain reaction and Western blotting. The probing depths remained the same over the 12 months. Failed implants totaled 96, resulting in an overall survival rate of 93.1%. From day 0 to day 14, no significant changes in GCF PGE2 concentrations were detected in either study group (P > 0.05). It was not detectable in a healthy site. All of them had 4 to 8 mm loss of attachment at minimally one site, but the typical clinical description of localized juvenile periodontitis was an exclusion criterion in this study. The relative benefit of CHX irrigation in comparison with CHX rinsing, water irrigation, and normal oral hygiene was evaluated. The mean concentration of AZM at all observed periods (baseline to 28 days) provided sufficient antimicrobial activity (>2 microg/ml) and fulfilled the conditions for a controlled-release device. A defect of increasing size was made at one site of the alveolar bone in a human skull. Eight rats were made chemically diabetic in order to study the tissue distribution of insulin I125. Rat molars with periodontium were perfusion- and post-fixed, decalcified, and frozen-sectioned. The multivariate analysis of variance test was used for statistical evaluation. Accuracy of cone beam computed tomography for periodontal defect measurements. Journal of Oral Pathology and Medicine, The present study evaluates the effect of two different hydrocortisone concentrations on mRNA expression of matrix metalloproteinases (MMPs) and tissue inhibitor of matrix metalloproteinases (TIMPs) in cultured, human gingival fibroblasts. There are no comparisons of concentrations of interleukin (IL)-13 and -15 and gingival sulcular depth within healthy or inflamed gingiva. (ABSTRACT TRUNCATED AT 250 WORDS). After 3 days, the plaque growth was assessed using the Quigley and Hein plaque index (Q&H PI) at six sites per tooth. Periodontology 2000, Abstract Objective: Clinical effects of periodontal treatment on biochemical and clinical Applications of heat and trypsin on the cell surface, strikingly reduced the binding ability. Subjects rinsing with chlorhexidine showed significant reductions of anaerobes, aerobes, and S. mutans in saliva. All oral tissues studied except dentin showed insulin I125 uptake. Bjorn Technique*, Alveolar Bone Mass Using 125 I Absorptiometry, Relationship Between Alveolar Bone Measured by 125 I Absorptiometry With Analysis of Standardized Radiographs: 1. Abbreviation, It has been shown that patients with localized juvenile periodontitis (LJP) often harbor Actinobacillus actinomycetemcomitans in the subgingival area. 24 2020: v.24(1): 1–91 Jan-Feb 2020: v.24(2): 93–185 Mar-Apr 2020: v.24(3): 187–294 May-Jun 2020: v.24(4): 297–391 Jul-Aug 2020: Vol. Gingival IL-6 concentration correlated significantly with the adjacent gingival sulcular depth, whereas the IL-15 concentration correlated inversely with the adjacent gingival sulcular depth (P <0.001). The dual rinses with 0.12% CHX immediately reduced the salivary bacterial load 97% and this reduction persisted for 60 minutes during S&RP. All 5 responded well to initial treatment. At 30 minutes and at 60 minutes aerobic bacteria were reduced 77% compared to control, and 96% compared to baseline. After 4 weeks an increase in the alveolar bone mass is noted and found to continue during the subsequent months. Two cases were peripheral reparative giant cell granulomas; eight were peripheral odontogenic fibromas; 41 were inflammatory hyperplasias; 68 were pyogenic granulomas; 11 were "hard fibromas"; one lesion exhibited the histologic features of a true fibroma. r Blackwell Munksgaard, 2005. January - December 2019 The editors and the authors of the papers submitted to the Journal … Implantation is currently the best option for tooth replacement in periodontitis. J Clin Periodontol 2011;38:856–863. In the present study we evaluated the prevalence and the degree of GO in a group of Italian renal transplant patients and the possible relationship between gingival lesions and demographic, oral, systemic, and pharmacological variables. Although significant (P less than or equal to 0.05), pocket probing depth reduction was minimal after CHX irrigation (4.6%). Compared to radiographs, the three-dimensional capability of CBCT offers a significant advantage because all defects can be detected and quantified. Fourteen dental students participated in a double-blind cross-over study. The average implant length was 13.3 mm, ranging from 8 to 16 mm. The 222 patients enrolled in the study were assigned to one of four groups: Group 1: Once daily irrigation with 300 ml water followed by irrigation with 200 ml 0.06% chlorhexidine gluconate (experimental); Group 2: Twice daily rinsing with 15 ml 0.12% chlorhexidine (positive control); Group 3: Once daily irrigation with 500 ml water (irrigation control) and Group 4: Sodium fluoride dentifrice for normal oral hygiene only (negative control). General descriptive bacteriological cultural analysis and assays for specific microbial populations were carried out. On the basis of clinical and microbiological parameters the 11 patients could be assigned to 1 of 2 groups. There were clinically and statistically significantly lower plaque and bleeding scores at the end of the chlorhexidine compared to the placebo period. The signal intensities of t-eNOS, p-eNOS at Ser1177 and Ser116 in the ERM were measured by densitometry and statistically analyzed. Patients were then assigned to either the chlorhexidine or essential oil mouthrinse group. Six cases had moderate periodontal breakdown with loss of attachment at 7 to 44 sites. (4) Journal supplement Mastri AR. ISSN: 0022-3492. Publishers own the rights to the articles in their journals. J Clin Periodontol 2012;39:688–697. Both disk gel electrophoresis and sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed that the purified product was homogeneous. All groups received the same sodium fluoride dentifrice for tooth brushing. All groups used the same sodium fluoride dentifrice for tooth brushing. An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic. All microbiologic categories showed significant improvement in both groups, with greater improvement in the test group. Br Med J 1981; 283: 628-635. Amplification refractory mutation system polymerase chain reaction (ARMS-PCR) was used for genotyping IL-10 polymorphism. Total antioxidant/oxidant status in chronic periodontitis patients with type II diabetes […] Samples were immediately diluted in transport fluid containing a CHX-neutralizer and then plated on trypticase soy agar for enumeration of the total aerobic and facultative bacterial load. Each surgical site received periodontal dressing and patients were given a placebo or CHx mouthrinse to be used twice each day. The Journal Impact 2019-2020 of Journal of Periodontology is In addition, supragingival plaque samples were obtained and analyzed by darkfield microscopy. Q1. J Periodontol. IL-2, -4, -6, -10, and -13 and IFN-gamma concentrations were higher within gingiva adjacent to 3 to 6 mm diseased compared to normal; IL-15 concentrations were significantly greater within normal gingiva than within diseased gingiva (P <0.001). RANTES concentrations were significantly greater in gingiva adjacent to > or = 6 mm pockets than in tissues derived from other sites (P < 0.001). J Periodontol. The epithelial rests of Malassez (ERM) are derived from the Hertwig's epithelial root sheath during tooth development. The other group consisted of 5 cases with relatively minor periodontal breakdown; i.e, 1 or 2 sites with 4 to 6 mm loss of attachment. THE BJORN TECHNIQUE is widely used in periodontal studies as a standardized measure of alveolar bone. Probing pocket depth and attachment level changes were not significantly different between both groups. At the end of the placebo and active treatment periods 1) saliva samples were taken and cultivated on a series of media; 2) the degree of gingivitis was assessed with gingival crevicular fluid (GCF) and gingivitis index (GI); and 3) the plaque index was assessed and the stainable buccal plaque extension was analyzed planimetrically. There were significant (r=0.308 to 0.835; P<0.05) correlations between the discolorations of tongue and tooth surfaces reported by the patients and clinically detected at all evaluation periods. Recently, we have found that a proline-rich and basic glycoprotein (MGP) from human parotid saliva, which is successfully purified by Concanavalin A-Sepharose affinity chromatography, binds to some oral streptococci such as S. mitis and S. sanguis. Rosa Maria J. Rodrigues, Cristiane Gonçalves, Renata Souto, Eduardo Jorge Feres‐Filho, Milton Uzeda and Ana Paula V. Colombo, Antibiotic resistance profile of the subgingival microbiota following systemic or local tetracycline therapy, Journal of Clinical Periodontology, 31, 6, (420-427), (2004). The Journal of Periodontology publishes articles relevant to the science and practice of periodontics and related areas. These data suggest that the -1082*A allele could be a risk factor for gingivitis. (ABSTRACT TRUNCATED AT 250 WORDS). An increased risk of having gingivitis was found in allele A positive children (G/A, A/A); 75% versus 25% in allele A negative children (G/G); (P = 0.01). Journal of Periodontology is a Subscription-based (non-OA) Journal. The aim of this study was to test whether 0.12% CHX spray was as effective as 0.2% CHX spray and 0.2% CHX mouthwash in a 3-day "de novo" plaque formation model. The dogs were divided into 3 treatment groups and one control group. Also, allele A positive children were at increased odds of having gingivitis of 1.8 (95% confidence interval [CI]: 1.05 to 3.06) compared to allele A negative children after adjusting for plaque, age, and gender. J Clin Periodontol. 77: 1261-1266, Histopathology of the Human Gingiva (Study based on 1269 Biopsies), Re: Gingival plasma cell granuloma. Journal of Periodontology Impact Factor, IF, number of article, detailed information and journal factor. To achieve the same effectiveness as a mouthwash, a higher dose (number of puffs) of CHX spray may be necessary. Recording the presence or absence of gingival inflammation chlorhexidine is both effective and acceptable oral health and 88 % chlorhexidine. -1082 * G were 45 % and 55 %, respectively implant are periodontitis. The photon source to a prefabricated precision-made occlusal splint molar and premolar teeth biochemical analyses were subsequent! 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Least 1 month elapsed before the second flap procedure was performed using the alternate group ligatures the... Participants had their teeth professionally cleaned on day 0 paper deals with some inhibitors which the!